Transfusion Service

AM23-ST-11-L - Perfusion, Not Transfusion: Providing Blood Products for Organ Perfusion Before Transplantation

Saturday, October 14, 2023

10:00 AM - 11:00 AM CT

Location: Grand Ballroom A2

CE: 1.0 CME (AMA Physician Credit) / 1.0 CE (Non-Physician Credit)

Program Chair(s)

EA

Elizabeth S. Allen, MD

Associate Professor of Pathology
University of California San Diego, California, United States

Disclosure(s): No financial relationships to disclose

Speaker(s)

Heidi Yeh, MD (she/her/hers)

Associate Professor of Surgery; Surgical Director of Pediatric Transplant
Harvard Medical School; Massachusetts General Hospital
Boston, Massachusetts, United States

Disclosure(s): No financial relationships to disclose
Laura D. Stephens, MD

Associate Professor; Associate Medical Director
University of California San Diego
San Diego, California, United States

Disclosure(s): Global Blood Therapeutics, Inc. (Dr. Fasano): Consultant/Advisory Board (Terminated, July 10, 2022)

Disclosure(s):

Elizabeth S. Allen, MD: No financial relationships to disclose

Heidi Yeh, MD: No financial relationships to disclose

Laura D. Stephens, MD: Global Blood Therapeutics, Inc. (Dr. Fasano): Consultant/Advisory Board (Terminated, July 10, 2022)

Session Description: Transfusion services typically issue blood to patients. Using new devices for normothermic perfusion of donor organs before transplantation presents opportunities for transfusion services to provide blood for organ perfusion rather than transfusion. These perfusion devices and techniques are poised to increase, as clinical trials have found them beneficial in increasing transplantations and reducing post-transplant complications. The process differs from routine hospital-based transfusions; the transfusion service from the transplant recipient’s hospital provides blood products to its organ procurement team, which utilizes them in organ procurement at the donor hospital and ex vivo perfusion before transplant. Accordingly, special procedures for blood product record-keeping, logistics, transportation, and billing are required. This session will review the provision of blood for organ perfusion from both transplant surgery and transfusion service perspectives.

Learning Objectives:

Describe the role of blood products in normothermic organ perfusion
List the solid organs for which normothermic perfusion prior to transplantation has been employed
Examine logistical and documentation requirements for transfusion services providing blood products for normothermic organ perfusion